The Plug Catcher Guide Shoe contains a plug to isolate the wellbore pressure from the coil tubing ID during run-in. After hang-off of the string, air, N2 or fluid pressure is introduced through the production valve at surface to overbalance bottom hole pressure to pump off the plug. The plug falls to the bottom of the catcher cavity, allowing production through the ports and up the coiled tubing string. Because the plug is retained in the catcher cavity, it will not interfere with the function or removal of equipment farther down the wellbore.